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Scientific articles and studies

IMPORTANT NOTE:

The following articles and publications are for educational and informational purposes only. They are not intended to be used by doctors, other practitioners, patients or clients to diagnose, treat or prevent any disease. Cancer diagnosis, treatment or advice in connection with treatment can only be given by a registered medical practitioner or oncologist.

Publications on maintrac

Published in the year: 2023
Authors:
Matthias Mäurer, Dorothea Schott, Monika Pizon, Sonia Drozdz , Thomas Wendt, Andrea Wittig, Katharina Pachmann
Title:
Increased Circulating Epithelial Tumor Cells (CETC/CTC) over the Course of Adjuvant Radiotherapy Is a Predictor of Less Favorable Outcome in Patients with Early-Stage Breast Cancer
Published in Medium:
Curr. Oncol. 2023, 30(1), 261-273;
Published in the year: 2022
Authors:
Monika Pizon, Dorothea Schott, Ulrich Pachmann, Rainer Schobert, Marek Pizon, Marta Wozniak, Rafal Bobinski and Katharina Pachmann
Title:
Chick Chorioallantoic Membrane (CAM) Assays as a Model of Patient-Derived Xenografts from Circulating Cancer Stem Cells (cCSCs) in Breast Cancer Patients
Published in Medium:
Cancers 2022, 14, 1476
Published in the year: 2021
Authors:
Madeleine Gold, Katharina Pachmann, Alexander Kiani, Rainer Schobert
Title:
Monitoring of circulating epithelial tumor cells using the Maintrac® method and its potential benefit for the treatment of patients with colorectal cancer
Published in Medium:
Molecular and Clinical Oncology

 

 

 

 Published in the year: 2020
Authors:
Pachmann, K.
Title:
Brustkrebstherapie in Zeiten der Covid-19-Pandemie.
Published in Medium:
Gyne 2020, 3:32-33

 

Published in the year: 2020
Authors:
Petra Payer, Michael Röder, Oumar Camara, Katharina Pachmann
Title:
High depletion of breast cancer cells from the peripheral blood with the method of non-specific separation
Published in Medium:
ecancer.org

 

Published in the year: 2019
Authors:
Pachmann K, Pachmann U.
Title:
Brustkrebs und endokrine Therapie: zirkulierende Tumorzellen als wichtiges Entscheidungskriterium.
Published in Medium:
Gyne 2019, 5:12-14

 

Published in the year: 2019
Authors:
Agrawal S, Wozniak M, Luc M, Makuch S, Pielka E, Agrawal AK, Wietrzyk J, Banach J, Gamian A, Pizon M, Ziolkowski P.
Title:
Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulation PIK3CA and GRB2.
Published in Medium:
PIK3CA and GRB2. Scientific reports 2019, 9: 16647

 

Published in the year: 2018
Authors:
Pachmann K, Henneking
Title:
Zirkulierende epitheliale Tumorzellen und Tumorstammzellen – Über ihren derzeitigen und zukünftigen Gebrauch bei der Überwachung des Krankheitsverlaufs von Krebspatienten.
Published in Medium:
Forum Komplementäre Onkologie, 2018, 5

 

Published in the year: 2018
Authors:
Pachmann K, Willecke-Hochmuth R, Schneider K, Kaatz M.
Title:
Circulating epithelial tumor cells as a prognostic tool for malignant melanoma.
Published in Medium:
Melanoma Res, 2018, 28:37-43

 

Published in the year: 2018
Authors:
Pizon M, Lux D, Pachmann U, Pachmann K, Schott D.
Title:
Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer.
Published in Medium:
Transl Med 2018, 16(1):356

 

Published in the year: 2018
Authors:
Pizon M, Schott D, Pachmann U, Pachmann K.
Title:
Tumorspheres cultured from peripheral blood as a biomarker for presence of metastatic disease in patients with breast cancer.
Published in Medium:
Personalized Oncology 2018, 2:65-73

 

Published in the year: 2018
Authors:
Katharina Pachmann, Stefan Schuster
Title:
The Value of Monitoring the Behavior of Circulating Tumor Cells at the End of Endocrine Therapy in Breast Cancer Patients
Published in Medium:
Cancers 2018, 10, 407

 

Published in the year: 2017
Authors:
Schott D, Pizon M, Schuster S, Pachmann K.
Title:
Häufigkeit und Relevanz von PD-L1/2 auf zirkulierenden Tumorellen in der Immuntherapie des Mammakarzinoms.
Published in Medium:
Onkologie heute, 2017, 6:40-42

 

Published in the year: 2017
Authors:
Pizon M, Schott D, Pachmann U, Pachmann K.
Title:
Determination of PD-L1 positive CETCs as a biomarker for PD-1/PD-L1 treatment monitoring.
Published in Medium:
Oncol Res Treat 2017, 40(suppl 3): 89 #P310

 

Published in the year: 2017
Authors:
Schott D, Pizon M, Pachmann U, Pachmann K.
Title:
Sensitive detection of PD-L1 expression on circulatinge epithelial tumor cells (CETC) could be a potential biomarker to select patients for treatment with PD-1/PD-L1 inhibitors in early and metastatic solid tumors.
Published in Medium:
DOI:doi.org/10.18632/oncotarget.20346

 

Published in the year: 2017
Authors:
Schott D, Pizon M, Schuster S, Pachmann K.
Title:
Häufigkeit und Relevanz von PD-L1/2 auf zirkulierenden Tumorzellen in der Immuntherapie bei Brustkrebspatientinnen.
Published in Medium:
Gyne 2017, 2:26-28

 

Published in the year: 2016
Authors:
Schott D, Pizon M, Pachmann U, Pachmann K.
Title:
Comparison of phenotype and gene expression analysis of circulating epithelial tumor cells (CETCs) and tumorspheres in colorectal cancer patients.
Published in Medium:
Oncol Res Treat 2016, 39(suppl 2): 272 #P897

 

Published in the year: 2016
Authors:
Pizon M, Schott D, Pachmann U, Pachmann K.
Title:
The number of tumorspheres cultured from CETCs in breast cancer patients is directly related to stage of disease and administration of chemotherapy.
Published in Medium:
Ann Oncol 2016, 27(suppl 6): p534, #1545P
Published in the year: 2016
Authors:
Regina Willecke-Hochmuth, Katharina Pachmann, Joachim Drevs
Title:
Treatment of advanced solid tumours with NSAIDs: Correlation of quantitative monitoring of circulating tumour cells and positron emission tomography‑computed tomography imaging
Published in Medium:
ONCOLOGY LETTERS 12: 1711-1716, 2016
Published in the year: 2016
Authors:
Pizon M, Schott D, Pachmann K, Pachmann U.
Title:
The number of tumorspheres cultured from peripheral blood is a predictor for presence of metastasis in patients with breast cancer.
Published in Medium:
Oncotarget, Advance Publications 2016, doi:
Published in the year: 2016
Authors:
Schuster S, Pachmann K.
Title:
Zirkulierende epitheliale Tumorzellen: Echtzeitkontrolle in der adjuvanten Krebstherapie, der Erhaltungstherapie und Langzeitüberwachung.
Published in Medium:
DZKF 2016, 1:46-50
Published in the year: 2016
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann K.
Title:
Frequent expression of PDL-1 on circulating epithelial tumor cells (CETCs) could be a new therapeutic target in breast cancer patients.
Published in Medium:
Oncol Res Treat 2016, 39(suppl1):D0303

 

Published in the year: 2016
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann K.
Title:
PDL-1 is more frequently expressed on circulating epithelial tumor cells (CETCs) in metastatic breast cancer patients and could be a crucial factor in the inhibition of immune response to CETCs during metastatsis formation.
Published in Medium:
Molecular Cancer Therapeutics 2016, #B95

 

Published in the year: 2016
Authors:
Zimon D, Pizon M, Mayer V, Pachmann K.
Title:
Stem cell markers are overexpressed in tumorsheres cultured from circulating epithelial tumor cells (CETCs) in patients with breast cancer.
Published in Medium:
Cancer Res 2016, 76:P3-07-59, doi: 10.1158/1538-7445.SABCS 15-P3-07-59

 

Published in the year: 2015
Authors:
Zimon D, Pizon M, Maier V, Pachmann U, Pachmann K.
Title:
Tumorsphären, die aus CETCs von Patienten mit soliden Tumoren kultiviert wurden, zeigen eine überexpression von Stammzellmarkern.
Published in Medium:
Oncol Res Treatment 2015, 38 (suppl 5): 1-288 (P-502)

 

Published in the year: 2015
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann K.
Title:
Die Anzahl der aus CECTs kultivierten Tumorsphären hängt von dem Stadium der Krankheit und dem Einsatz einer Chemotherapie ab.
Published in Medium:
Oncol Res Treatment 2015, 38 (suppl 5): 1-288 (V-631)

 

Published in the year: 2015
Authors:
Pizon M, Zimon D, Maier V, Pachmann U, Pachmann K.
Title:
PDL-1 is highly expressed on circulating epithelial tumor cells (CETCs) and could ba a crucial factor in the inhibition of immune response to CETCs during metastasis formation.
Published in Medium:
EJC 2015, 51 (suppl 3): p 18-19
Published in the year: 2015
Authors:
Zimon D, Pizon M, Pachmann U, Pachmann K.
Title:
Characterisation of tumorspheres cultured from circulating epithelial tumor cells (CETCs) in pancreatic cancer patients.
Published in Medium:
EJC 2015, 51 (suppl 3): p6
Published in the year: 2015
Authors:
Zimon D, Pizon M, Stein EL, Pachman UA, Pachmann K.
Title:
Vemurafenib to eliminate BRAF-mutated circulating epithelial tumor cells (CETCs) from blood of patients with malignant melanoma.
Published in Medium:
J Clin Oncol 2015, 33 (suppl; abstr e11031)
Published in the year: 2015
Authors:
Pizon M, Zimon D, Pachmann UA, Pachmann K.
Title:
Tumorspheres cultured from circulating epithelial tumor cells (CETCs) in pancreatic cancer patients having cancer stem cells properties and resistance to standard chemotherapeutics.
Published in Medium:
J Clin Oncol 2015, 33 (suppl; abstr e22031)
Published in the year: 2015
Authors:
Pizon M, Zimon D, Pachmann UA, Pachmann K.
Title:
The number of tumorspheres cultured from CETCs in breast cancer patients in relation to stage of the disease and administration of chemotherapy.
Published in Medium:
J Clin Oncol 2015, 33 (suppl; abstr e22032)
Published in the year: 2015
Authors:
Pachmann K, Schuster, S.
Title:
Brustkrebs-Überwachung nach Ende der Hormontherapie: Bieten zirkulierende epitheliale Tumorzellen eine Entscheidungshilfe?
Published in Medium:
Gyne 2015, 05:28-32
Published in the year: 2015
Authors:
Pachmann K, Schuster S.
Title:
Brustkrebsüberwachung: Bieten zirkulierende epitheliale Tumorzellen eine Entscheidungshilfe?
Published in Medium:
DZKF 2015, 3:15-19
Published in the year: 2015
Authors:
Guntinas-Lichius O, Pachmann K.
Title:
Zirkulierende Tumorzellen bei Kopf-Hals-Tumoren.
Published in Medium:
DOI 10.1055/s-0035-1548921, Laryngo-Rhino-Otol 2015, 94:367-73
Published in the year: 2015
Authors:
Pachmann K.
Title:
Wie beeinflußt die Therapie solider epithelialer Tumore die im Blut zirkulierenden Tumorzellen.
Published in Medium:
DZO 2015, 47:82-87
Published in the year: 2015
Authors:
Pachmann K.
Title:
Current and potential use of MAINTRAC method for cancer diagnosis and Prediction of metastasis.
Published in Medium:
Expert Rev Mol Diagn
Published in the year: 2015
Authors:
Inhestern J, Oertel K, Stemmann V,Schmalenberg H, Dietz A, Rotter N, Veit J, Goerner M, Sudhoffs H, Junghans C, Wittekindt C, Pachmann K, Guntinas-Lichius O.
Title:
Prognostic Role of Circulating Tumor Cells during Induction Chemotherapy Followed by Curative Surgery Combined with Postoperative Radiotherapy in Patients with Locally Advanced Oral and Oropharyngeal Squamous Cell Cancer.
Published in Medium:
PLoS One
Published in the year: 2014
Authors:
Mahal K, Schill E, Breyer S, Pachmann U, Pachmann K, Schobert R, Biersack B.
Title:
Acitivity of a Doxorubicin Menthol Conjugate against Circulating Epithelial Tumor Cells of Cancer Patients.
Published in Medium:
J Pharm Sci Pharmacol 2014, 2:1-4, DOI:10.1166/jpsp.2014.1027

 

Published in the year: 2014
Authors:
Zimon D, Pizon M, Stein EL, Pachmann U, Pachmann K.
Title:
Differential chemosensitivity between CETCs and tumour spherodis in cancer patients with solid tumors.
Published in Medium:
Europ J Cancer 2014, 50(suppl 6):62, #190

 

Published in the year: 2014
Authors:
Winkens T, Pachmann K, Fressmeyer M.
Title:
The influence of radioiodine therapy on the number of circulating epitzelial cells (CEC) in patients with differentiated thyroid carcioma – a pilot study.
Published in Medium:
Exp Clin Endocrinol Diabetes 2014, 122: 246-253
Published in the year: 2014
Authors:
Pachmann K, Zimon D, Pizon M, Pachmann U.
Title:
Tumor spheres growing from peripherally circulating tumor cells exhibit stem cell features.
Published in Medium:
Cancer Res December 15, 2013 73:PD6-1; doi:10.1158/0008-5472.SABCS13-PD6-1
Published in the year: 2014
Authors:
Pachmann K.
Title:
Tumorspheres cutured from circulating epithelial tumor cells (CETCs) as diagnostic marker in patients with solid cancers.
Published in Medium:
J Clin Oncol 2014, 32:705, #11043

 

Published in the year: 2014
Authors:
Pachmann K.
Title:
Comparison of chemosensitivity testing of CETCs and spheroids in cancer patients with solid tumors.
Published in Medium:
J Clin Oncol 2014, 32:166, #2598

 

Published in the year: 2014
Authors:
Pachmann K, Pizon M, Zimon D, Stein EL.
Title:
Somatic mutations of the EGFR, KRAS and BRAF genes: Heterogeneity in circulating epithelial tumor cells (CETC) as determined using the Cobas Z480 analyzer.
Published in Medium:
Europ J Cancer 2013, 49(suppl.4):34(#MC13-0080)
Published in the year: 2014
Authors:
Zimon D, Pizon M, Pachmann U, Pachmann, Pachmann K.
Title:
Determining the role of IGF-IR and VEGFR-2 in the development of resistance to trastuzumab in breast cancer.
Published in Medium:
Oncol Res Treat 2014, 37 (suppl 5):262(#P798)
Published in the year: 2014
Authors:
Pizon M, Zimon D, Pachmann U, Pachmann, Pachmann K
Title:
In vitro chemosensitivity testing of spheroids cultured from CETCs of cancer patients with solid tumors.
Published in Medium:
Oncol Res Treat 2014, 37 (suppl 5):271(#P822)
Published in the year: 2014
Authors:
Zuerch M, Foertsch S, Matzas M, Pachmann K, Kuth R.
Title:
Cancer cell classification with coherent diffraction imaging using an extreme ultraviolet radiation source.
Published in Medium:
J. Med. Imag. 1(3), 031008 (Oct 03, 2014). doi:10.1117/1.JMI.1.3.031008
Published in the year: 2014
Authors:
Sorg S, Pachmann K, Brede-Hekimian K, Freesmeyer M, Winkens T.
Title:
Determining tissue origin of circulating epithelial cells (CEC) in patients with differentiated thyroid cancer by real-time PCR using thyroid mRNA probes.
Published in Medium:
Cancer Letters. dx.doi.org./10.1016/j.canlet.2014.09.046
Published in the year: 2014
Authors:
D. Zimon, M. Pizon, U. Pachmann, K. Pachmann
Title:
A SUBPOPULATION AMONG CIRCULATING EPITHELIAL TUMOR CELLS IN PATIENTS WITH SOLID CANCER IS CAPABLE OF SPHERE FORMATION AND CARRIES CANCER STEM CELL PROPERTIES
Published in Medium:
Poster Abstracts – IFCC WorldLab Istanbul 2014 – Istanbul, 22-26 June 2014 – DOI 10.1515/cclm-2014-4013 Clin Chem Lab Med 2014; 52, Special Suppl, pp S1 – S1760, June 2014 – Copyright by Walter de Gruyter – Berlin – Boston S436
Published in the year: 2014
Authors:
D. Zimon, M. Pizon, U. Pachmann, K. Pachmann
Title:
EGFR, KRAS AND BRAF MUTATION ANALYSIS IN INDIVIDUALLY DEPOSITED SINGLE CIRCULATING EPITHELIAL TUMOR CELLS (CETCS) USING THE COBAS Z 480 ANALYZER
Published in Medium:
Poster Abstracts – IFCC WorldLab Istanbul 2014 – Istanbul, 22-26 June 2014 – DOI 10.1515/cclm-2014-4013 Clin Chem Lab Med 2014; 52, Special Suppl, pp S1 – S1760, June 2014 – Copyright by Walter de Gruyter – Berlin – Boston S387